Depends on what you want out of your system. Twins aren't just for all out race cars!!! Twins are common place now days on many new vehicles. They don't go that route for all out monster power!. They do it with two smaller than normal turbos and can then reduce turbo lag to "literally zero". Yes, I've found this to be true, not on my Buick, but rather my Lincoln. And they don't use any fancy high stall converters to achieve it either. Full boost is there instantly!!
Granted, the expense of doing this on a 25 year old Buick might be a bit much to swallow, but if a person were an expert fabricator/welder, it could be done reasonably. The advantage of twin turbos (one per bank) is, contrary to what has been said is huge. You can use much smaller turbos, and still achieve the same power level, and reduce lag to nothing.
Sure, the big twins you see on Buick race cars aren't there for driveability, but rather ground ripping power.
So, if you wanted to go twins, you can see that there are two distinct routes one could take in the design and fabrication.