How much tuning do you want to do?.
If you content to try and run the injectors static, then you can run that way for a while.
But, see you mentioned that ugly word Safely.
If you want to run Safely then you'll want to go by the well established rules where you don't go over 85-90% DC and that means big injectors.
You might look at the Direct Scan run files on accessible from the Scan Tool Section, and look at the %DC of some 11 sec cars and see what you think.
RC Engineering has a few good words on the DC stuff.