from erics site : works like my 5.7 chip, except there are more adjustable features. It also can read the wideband reading from the Powerlogger and do corrections. In the chip, you have three target A/F adjustments, mid boost (3-14psi), WOT 1/2 gear, WOT 3/4 gear. If you set an A/F of 11.5, it will try to maintain that as best it can based on info from your wideband. You have to make sure your wideband is working properly so you don't get false info (garbage in, garbage out as they say). The program can add up to 33% fuel, and subtract 10% fuel to maintain the A/F. You can adjust the base WOT fuel to keep the correction inside the "window". I limited the subtraction to 10% so it can't get too crazy pulling fuel if something wrong happens.
So based of that the only reason you would need to change your WOT fuel is to keep it inside the 33% window.