on my car, the 255/50 rubbed a little bit on the front tires when i turned the steering wheel all the way to full lock- it was just a very minor rub against the plastic inner fenderwells on both sides behind the tires right at full lock. the slightly narrower 245/50 on the very same rims doesn't rub at all.
every car is different, and yours may rub more, less, or not at all- or even be different from side to side. but i will say that the 255's looked flat out evil on the car, and if i could have found a tire in that size that was in my price range when i was shopping for tires, i would have gone with that size instead of the 245's. a slight amount of rubbing at full lock isn't an issue to me.