I ran 24psi and 24 degrees on AV gas (somewhere around 108 octane) with no knock. Don't know if you need this since it was with an intercooler but I had the basic mods like ported heads and intake, 206 cam, TA49, and a 2.5" DP.
My dad's car ran 25psi @ 28 degrees of timing on pump 100 octane and alky injection. There was an occasional count or two but never more than 2 degrees of retard and usually none. We were told that was no where near enough octane but it worked and the only time we hurt a headgasket was when the alky jet got plugged during a run.