This is very interesting and made me take a look at whats going on. While I agree once the injector is opened up then the pressure differential makes an impact with the fuel flow, the thing that needs to be looked at is differential pressures on the valve that opens the injector.
The 95lb Precision injectors are ball and seat design. The MSD 50s are too. Easy to find multiple references on the web where these designs don't like very high inlet pressures, like the 80psi limit the OP found. The pintle design doesn't seem to be affected as much. Looking at the designs I don't think the boost pressure on the outlet side has much to do with it and its probably a function of the valve design and the inlet pressure.
Why? Take a look at the two injector designs:
View attachment 260367
View attachment 260368
On the outlet sides of both injectors you only have a very small surface area seeing the boost coming from the manifold side. The size of the pintle nozzle is very small, and the holes on the director plate of the ball and seat injector are also very small. I don't think its going to add much force to the valve even if the boost was 50psi. Now on the inlet side coming from the fuel pump you not only have a larger surface area, its fluid. 80psi of fluid pressure on the inlet side of the injector on a larger surface area vs 30psi of air pressure on the outlet side over a very small area. I think the boost pressure has a minimal affect on the valve action.
Now when you look at the different designs, for the ball and seat style you got all this fluid surrounding the surface area of the ball working against it while the pintle nozzle being a cylinder the pressure is mainly coming from the sides and not working against it opening. At high inlet pressures it makes sense that the ball would be harder to unseat compared to the pintle nozzle.
Also coming into play would be the coil strength to lift the valve up. High Z injectors usually are weaker due to the lower current. So running high impedence ball and seat injectors at high boost would seem to be of more concern, for example the MSD 50s. Other high z injectors with bad designs or weak coils at high boost would be of concern too. The 96lb injectors are low z and should be better but as the OP found out they can fail too.
Obviously I'm just trying to figure out whats going on and there may be more to it, but its something I never looked at before but definitely has me thinking now. Just put a set of MSD 50s in my truck too darn it.