I upgraded my wife's car to 6 speakers + sub. It was easy but took alot of research. The factory stuff was ok but it would get buzzy and distorted so I switched it all out. The short version was this:
Installed 4 channel amp under pass seat.
Ran 2 rear channels left + right in normal parallel.
Ran 4 fronts (dash & door left + dash & door right) in series to keep the ohms from being too low.
Used aftermarket head unit but if factory was desired, I could have used line out converters.
Used 2 channel amp I already had for sub in hatch to power 8" sub.
Ebay can be your friend for an amp and a sub. I picked up a Kenwood KAC-943 for $80 shipped. Got the JL Audio 8" sub for about the same with shipping; they are heavy. I also used new JBL GTO speakers (4", 6" & 6x9" from
http://www.etronics.com ). For wiring,
http://www.knukonceptz.com is the absolute best & cheapest place to buy their Klarity RCA cords, fuses, wiring, etc. Knukonceptz has an ebay store also; their website was not working a little while ago. Both places have quick shipping and do what they say.
I ended up with about $425 in the whole system including the sub. Made my own box from scraps I had lying around so that kept the cost down. Bought gray felt at local fabric store.
You can do it right for cheap if you shop! Time is the biggest investment.