It depends
My experiences that a 93 chip with 91 Octane does not perform as well as 108 chip with Race Gas. But there are so many variables. Air Temperature, Car Set up, Track Conditions, Wheels, Tuning, etc.
I've had the most fun draining the tank and filling the car with the highest octane fuel I could find. Leaded will eventually destroy your O2 Sensor, but you can race all day. High Octane Unleaded will minimize detonation. etc.
There are many performance recipies on the net. Stick to those and only change one thing at a time and buy the best bolt ons when you can afford them. But you've got to be careful not to get a 70 series turbo with a stock torque converter/tranny for example.
Find some other buick racers in your area. There's always somebody faster to learn from.
Larry