Well having a perfect fuel curve would be, well perfect, but thats basically impossible because of many factors which will have an effect on A/F consisting of but not limited to: timing, engine temp, air temp, humidity, altitude, boost, intake air temp and so on. Thats where the wideband is a fantastic piece of equipment for helping to make automatic corrections based on those variables and showing you those corrections made so you can then correct your base tables.
You want a base fuel curve as close as possible obviously so the WB doesn't have to make large corrections. Think of it this way, if the WB is having to make a 20% correction at one point in the map then gets to a point where 0% correction or even negative correction is needed, well your going to have a transition period where the WB correction is removed which is a period of time where you'd be better off with a more consistant and correct base table so the A/F would stay closer to the target. So you do have something to gain with smaller WB corrections to the base tables, aka fewer transitional corrections periods. Not to mention the WB correction process is a toss up between being able to make fast corrections to get to target quickly to protect parts and being able to make small corrections once on target to maintain the target.
As for different boost levels or octane levels I would imagine more than one program would be suggested, low boost street octane and high boost race octane and anything inbetween depending of course on how you like to and mostly drive the car.
my 2 cents.
HTH