Just my opinion, we use 100 ft-lb's on main studs or bolts. Going to 110 or 120 ft-lbs may not hurt or help?
The weakest part of a production Buick V-6 block is the thin web from the crank mainline to the cam tunnel, and we have seen a couple dozen or more blocks give up there, usually in the threaded holes for the main bolts.
At that point the block is trashed, as even with weld repair, structural integrity is compromised?
Stage blocks and the TA alum block has much more "meat" in that area which helps reliability greatly at increased HP levels, but we still use 100 ft-lbs.