Hmm. Well of course all roller chains are not equal. Lots of Chinese junk out there that "looks" ok, but isn't. That's why I have always stuck with a Cloyes Tru-roller chain and gears for my V8 SBC engines. One of those redlined at 8000 moving a 0.580/0.600 lift cam. Notionally, I would guess that the stress on the chain has to be smaller when moving 12 lifters instead of 16. And the intended redline for my V6 is only going to be about 5400 with relatively mild valve lift under 0.500". That is why I momentarily considered using a factory nylon chain. I will certainly go with the experience of this group though and look for a Cloyes - if they even make one for a Buick 3.8...
Umm no. Not the v6's i was referring to. No Chinese junk and well over 7000 rpm and .700 lift. They had rollmasters on them and they surely arent Chinese junk. They are the best timing sets ive ever seen. At least as good as a Cloyes. Any hard running iron headed stock block will be fine with a Cloyes or any of the available roller sets. Ive ran them all from Edelbrock to Cloyes to Rollmaster. Im not against the factory chain at all. Never seen one of those fail even after running on a stock nylon tooth gear that had 70% of its teeth gone.