Well that depends. If by 'manually lock it' you mean locking it where the stock chip would otherwise not allow it to lock (i.e., at WOT) then yes you should see a huge difference.
If by 'manually lock it' you mean versus an aftermarket chip that would lock it at WOT then no, there would be no difference. Locking is locking whether it's done manually or by the chip.
Unless you have a chip programmed to lock at a certain MPH, the converter will not lock at WOT. In that case a manual lock will lock the converter and you should see it in the slippage calculation.
9% is not too bad for a D5. I had 13% with a D5 that went 102.9mph in the eighth and 124 in the quarter long ago for a power comparison to yours and mine wasnt horrible either considering it was dealing with 600+ft lbs being thrown into it. To get less you will need a higher dollar custom unit. The converter in my sig is around 12% on the 126mph run. A little too much for what it is imo.