Providing you have a flat tappet cam That is right. The cam lobes must be off center of the lifter bores to make the lifter spin in its bore. If you look at #3 exhaust lobe it will be usually centered over the lifter bore. Cam manufacturer have to put a reverse lobe taper on that lobe to make the lifter spin. If you ever have your valve covers off and watch the pushrods #3 exhaust will rotate in the opposite direction than the rest of them.
Hope this helps!
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1986 Buick Regal T-type
STOCK
DK. Blue Metallic w/tan interior