If you are below 15# of boost you should not be seeing any knock at all no matter what gear your in.... Now if you are at part throttle and 10-15# of boost, thats a different story than WOT because part of your Power Enrichment fueling is based on TPS. If you are only at 2.5v TPS, you may be only getting 50% of the total PE fueling, which may be causing you to run lean for that moment, if the MAF is maxxd out at 15psi boost and you do not have an entender chip w/LT1 MAF....there's a lot of variables there.
So, if at 105 mph, you mash the pedal to WOT and get no knock, then your ok, car is running correctly, if you part throttle it and get iinto boost, then there's a lot of variables there that could cause a slight lean condition.
Now on the progressive alky. Progressive setups are better than non-progressives when it come to tuning..yes both can be setup to have no knock at whatever boost level you want to run at, but once the alky comes on in a non-progressive system, you will be running rich until max boost is reach provided you have tuned for max boost...reason is the alky amount/flow does not change from say a turn on point of 15# all the way up to 26#. And if your running a traditional setup where the MAF is maxxed out at around 16# boost, the fueling will not change much either....so the only thing changing is more air as boost increases to 26# from 16# finally reaching that "sweet spot" in the A/F at 26# of boost.
With a progressive system, you can tune it to a perfect A/R all the way up from 16# to 26# and produce the max power as boost is building by progressively adding more alky. Chip fueling also comes into play, but that can be a lengthy discussion...I'm assuming that the fueling is static once the MAF is maxxed which is around 16-18# normally.
M alky is set to come on around 5 psi and then ramp up with boost up to 24#.
Sometimes the transitional knock at the shifts is almost impossible to tune out depending on the car, that can be false knock as the motor rpms change speeds quickly.....put in some race fuel and see if it goes away to be certain.