It's not too bad at all, in just a little over an hour you can have them swapped out if you have done it 3-4 times before

A first timer will take you about 3-4 hours, not including IC removal and cleanout. Basically take off intake pipe, remove the cover, remove the J-bracket (it will take you longer to get the bottom bolt off of the J-bracket than to do anything else

) Remove the 2 bolts holding the oil drain, remove the oil feed, remove the IC hose, undo the DP, remove the 3 bolts to the header and your done.
When putting back together, the trouble areas will be getting the oil drain pipe reattached cause the PT61 housing is bigger than the stocker and the oil drain pipe has to twist around the compressor housing, so its a bit tighter, studs in the turbo will help lots for this.
Also, test fit the turbo to make sure the outlet matches up to the IC inlet, if not, loosen the compressor side bolts a little and "Clock" the compressor housing to match to IC inlet.
You may also have a bit of trouble getting the oil feed line back on, seems like on some turbos, the oil feed plate bolts are in the way in order to get a wrench on the nut to tighten the feed line. On a few turbos, I ended up removing the plate bolts and grinding the heads down some to give me enough clearence to get a wrench on the oil feed tube nut. Especially pay attention to how far you screw the 90 degree brass fitting down, because the further you tighten it down, the less clearence you will have.