TurboTweak is a very popular chip for our cars. I highly recommend these chips.
TurboTweak.com
Depending on your goals, the time to change injectors is when you buy your new chip. Stock injectors are done by the time you get into the 11's even with alky. I highly recommend if you want to go 11's and are about to pull the trigger on new injectors.... jump straight to the 60's. They work fine with a stock unmodified ECU and will work from a stock motor all the way to 10.0's or maybe a little quicker with alky.
You might need to decide what chip to get based on your computer skills. If you are not computer friendly and want a plug-n-play chip deal, then I would recommend the TT 5.7 chip and forgo the wideband controlled chip. You can always start there and get another chip later if you like...... The 5.7 chip has some adjustable features for fueling and timing that you can set using a scanmaster (which you can also get from Eric at TT). One of these setups will still get you into the 11's just like the wideband controlled chips.... The beauty of the wideband controlled chips is the chip can monitor the wideband and make fuel corrections at WOT to help keep your air/fuel ratio right on target. The 5.7 chip can't correct at WOT. You will want to pickup a scanmaster (as a minimum) if you choose to do the (non-wideband) 5.7 chip.
If you decide you are computer savy enough, and like the wideband idea.... you will need a couple extra pieces of hardware not required for the 5.7 chip. You will need the wideband (of course) and a powerlogger. The powerlogger is a datalogger that connects directly to the board of your ECU with some slight modification to the case of the ECU. It is the only means to get the wideband signal into the ECU so the wideband chip can tweak the fueling. The wideband Eric @ TT recommends is the AEM or the PLX wideband. These can be purchased through Summit or Jegs.
To properly take advantage of the wideband chip.... you will want to have a laptop available to make initial chip settings and datalog it.... and also for track trips. I run the scanmaster for daily driving...and bring in the laptop if I am tuning or going to the track.
For the turbo, I would suggest Cal Hartline - Hartline Performance or Mike Licht @ Full Throttle. I'd highly recommend Precision Turbo as the brand of turbo to buy unless you are getting a good used TE44 or TA49. These are identical turbos except the 49 has a "stock appearing" compressor housing with the bolt-on inlet bell and the TE44 has a slightly less restrictive compressor housing with integral inlet bell.
If you decide to go used.... look up Bison here on the board...... he is selling good used turbos and can hook you up with a turbo that will fit your needs.
Alkycontrol for the alky system. Julio is the man on these alky kits for a Turbo Buick.