If the current engine is the tried and true 2.5 liter "Iron Duke", then yes a 60 degree block would work. The S-10's of the 80's used the same trans on the 2.5 and 2.8 models, only the 4.3 liter had a different style bell housing.
I don't know if a 3.8 would work or not.
I have been told a 3.4 out of a 93-95 Camaro will work.