I've run it for some time on my Syclone, with stock lines. Also using a 340LPH pump with stock lines. The return line seems to flow much more than the Buicks, so no problems with maintaining low fuel pressure at idle and vacuum.
I would use a 340LPH pump if using the 80's, and you plan to go faster in the future. The 255LPH won't supply 80's properly if the duty cycle gets high enough.