There are pro's and con's to E85 so OP, make sure you are aware of some of the things to watch out for. But before you go converting due to E85's Winter blend........
1) Are you going to drive your S2 GN from November to March since you're in PA? I doubt it, hell I don't drive mine and it's not nearly as expensive as your engine.
2) 9:1 Compression with 22psi is not the same as most GN's at 8:1 on 93 and Alky unless you drop the timing
way out of it. This is an expensive S2 engine, I wouldn't run that fueling setup, it would need at least 100 octane as the fuel in the tank for me to take that financial risk.
3) How much more could he turn up the boost on Pump and Alky vs E85 and Alky with 9:1 compression? He has room to grow and all he needs to do is fill the Alky bottle and have at it around 24-25psi safely.
Make sure you drain the tank of E85 this Winter, don't allow any condensation to build up so just drain it. Make sure you don't have any aluminum fittings and keep an eye on your fuel filter regularly.
BTW, make sure this engine is no leaner than 10.8 AF/R on E85, if you add Alky it needs to go fatter.