Pardon me for playing devils advocate but with the specific gravity of methanol and the amount you are throwing at it, could the intercooler be chilling the meth to the point where it is not atomizing very well through the intake? Maybe its not an issue with a turbo stuffing the manifold.
But a shot of nitrous combined with methanol has to be cooling off things pretty well. Just thinking out loud here.
Which brings us back to the main question. How cold is too cold with methanol?
Let's take a look at an alcohol injected, naturally aspirated engine. How cold is the intake charge in that application? Air entering the engine is at atmospheric pressure. The temperature is ambient. Compression ratios of 16+:1 are used to heat the charge for proper vaporization during compression and combustion. I've never heard of anyone saying that ambient intake air temperature was too cold for a naturally aspirated, alcohol injected engine.
Now let's go back to an alcohol injected, turbocharged engine. At zero boost, the engine is basically following the same criteria as a naturally aspirated engine. The intercooler, unless it's been iced, is not heating or cooling the intake charge beyond ambient. We won't be getting the equivalent hp out of the engine though, due to the lower static CR that must be run because of the plan to boost the dynamic CR way above what any static CR could ever provide in a naturally aspirated only application. Due to the lower static CR of the turbocharged engine, at off boost operation the air/fuel charge won't be properly heated during compression and the resulting vaporization and power will suffer for it. Not terribly, but noticeably.
Now let's step up to boosted operation. We can't argue that as the turbo compresses intake air, it's being heated. The more boost, the more heat. The heat that is added is preheating the air before it enters the combustion chamber. In a low boost, low static CR situation, that added preheating of the intake air is helpful to vaporize the fuel. What is the intercooler doing to the intake charge temp at this point? It is cooling it. Possibly down close to ambient temps. Depending on how much boost we have at this point, it could be hurting us if the dynamic CR has not started to heat the air/fuel charge to a proper level for good vaporization of the fuel. This will hurt spool up time.
Now let's move to high boosted operation. The turbo is heating the intake charge to very high temps. Let's say 300 degrees F. Depending on where our static CR was set and the boost level, our dynamic CR is probably going through the roof! Much, much higher than any high compression, naturally aspirated, alcohol injected engine could ever dream of attaining. It can calculate out to 30+:1 in some static CR/boost combinations. How much heat is the dynamic CR at this high boost level adding to the air/fuel charge during the compression cycle now? It is a lot! And remember, we started out with air temps of over 300 degrees out of the turbo, then compressing that in the cylinder with a dynamic CR of over 30:1. Can anyone say, what's the autoignition temperature of methanol?
You have four choices to reduce air/fuel charge temps to below autoignition levels:
1)Reduce the static CR.
2)Reduce boost. Who wants to do that!
3)Add more methanol, which will act as a chemical intercooler for you. It will not be burned, because there are only so many oxygen molecules in the combustion chamber. In fact, the extra methanol will be taking up room in your combustion chamber that should be used for more of a balanced air/fuel charge. The extra fuel also makes ignition more of a problem. Magneto anyone?
4)Or, use an intercooler along with a less rich mixture. Still using the help of the chemical intercooler, because the intercooler can't do it all alone.
Who wants that intercooler now?