I have a 355 with a energizer crane cam a Edelbrock intake 194 heads an 750 holly carb
Limited smallblock
which Energizer cam?
which Edelbrock intake?
which 194 heads? could be anything from camel backs to smog era 882's to a set of Bowties..
which 750 Holley carb? looks like a 3310 from the pic, which is a good all around carb for a 400ish hp 355..
without knowing all that and assuming the carb has the same jets and power valve that it left the factory with, you can get a good general starting point by unhooking your vacuum advance and setting your initial timing at about 18 or so BTDC, then figure out a way to limit the total timing to about 36 or so- i do it by pulling the distributor completely apart and welding up the slots to limit the amount of advance, but there are other ways to do it that aren't so involved.. you might wind up with more or less initial and total timing, but those are good generic starting points for a typical small block.
hook the vacuum advance up to a port that has full manifold vacuum- you want 45-50 degrees of timing at idle, which helps with throttle response and fuel economy.
baseline the carb by backing out the idle speed screw until the throttle blades are fully closed, then putting about a turn of preload on it... gently bottom out the idle mixture screws on the sides of the front metering block and turn them 1.5 turns out.
when you start it, you might need to bump the idle speed up a bit to get your desired idle speed- but don't turn the speed screw too far since you are shooting for the throttle blades to be opened as little as possible at idle..
if everything is in working order, this should make it idle well enough to hook up the vacuum gauge and set the idle mixture screws for max vacuum at idle, preferably with the car in gear.. keep tweaking the screws and backing off the idle speed screw until you can't get it any better- you should have throttle response that rivals any modern efi equipped car once you get it dialed in, which means it will be faster off idle when you mash the gas...
then you can start playing with the secondary spring (get the quick change kit- it's worth it) and accelerator pump cam.