A few differences between port injecting or injecting with a single nozzle.
The first thing to realize is that nitrous absorbs heat energy from the surroundings as it changes state from a liquid to a gas. This is what gives it the cooling effect.
Nitrous is more dense in its liquid state. More oxygen content per volume.
Gaseous nitrous will distribute better that liquid nitrous.
In a single nozzle setup, it is important that the nitrous changes physical state before it has to make turns in your inlet tract. Liquid just doesn't make sharp turns as well as a gas.
When the nitrous changes state in the inlet tract, it will cool the overall inlet charge and make for a denser overall inlet charge.
Port injecting nitrous will have less of a cooling effect on the inlet tract, but will have a major cooling effect during the compression stroke, since much of the nitrous will enter the cylinder in liquid form and will be changing state inside the cylinder, cooling the combustion process more directly. Another fine point about port injecting nitrous. Since much of the nitrous is entering the cylinder in a liquid form, much denser than when its in a gaseous state, you end up with a supercharging effect of the charge as the nitrous changes state from liquid to gas directly in the cylinder.