I've done several DIY turbo builds on both GM and Ford set-ups. It's never as easy as it sounds.
Some of the hurdles:
Headers. Build your own, or try to find some shorties that you can flip around and point forward.
Tune. The stock TPI ECM (like in my 91 Corvette) has a MAP sensor that is limited to atmosphere. It won't detect pressure beyond atmospheric, so it won't add fuel appropriately. You can use a boost referencing regulator like the Buicks do, but the fuel system and engine management weren't designed to work that way so you are kind of playing with fire. You can make it work with a 2+ bar MAP sensor and tuning the computer, but there isn't a whole ton of people who have done it that way. If you aren't comfortable with chip tuning, there isn't really anyone you can call and ask for advice. You're on your own there.
Fuel system. The stock fuel system on just about any car won't support the HP levels you are talking about. You'll have to budget for pump, lines, rails, injectors, etc...
Drive train. Most drive train parts won't take the power you'll be laying down. Budget for transmission, clutch/converter, rear end, axles, U-joints, etc...
There is a ton more, but that's a taste.
Here's how I would do it on a chevy 350, assuming that space wasn't an issue and you could package all this stuff:
2 T3 .60/.63 turbos from E-bay.
2 shorty headers flipped around and pointing forward.
2 intercoolers from 2.3 litre Thunderbird S/C cars.
DFI from big stuff 3 if budget allows, or megasquirt if on a tight budget.
Turbo 400 auto or T56 manual.
That should be capable of 600 wheel HP and spool like a rocket.
Shoot me an email if you undertake the project.
joshkinzey@gmail.com