Most times we set the engine at #1 TDC by aligning the timing marks then install the new timing set. The dots on the timing gears to tell us that they are installed properly if we set #1 at TDC before installing the new timing set.
If you are talking about degreeing the cam, that's probably not necessary. This is done to determine if the camshaft is installed in the correct location relative to crankshaft rotation, and to check if it is made properly. The dots on your timing set will get you close enough. If you want to learn, degreeing the camshaft might be educational.