Been thinking about this topic from a different perspective. More power pulses per second is key to the destroked motor making more power. When comparing a 600 hp 231 @ 2.5 hp per cubic inch vs a 280 ci (at equal RPMs) the extra 50 ci is a huge difference in potential power.
Not really. More power pulses is a result of increased RPM, which may or may not be something you get from a destroked engine, depending on how you build the engine around the crank.
There are only a few direct effects of reducing the stroke:
1) Reduced displacement
2) Reduced piston speed
3) Crank rod pins are closer to centerline of the crank
What do you do with that? Reducing displacement is easy to overcome with forced induction. So we move on to #2. You can calculate the benefit there:
http://www.csgnetwork.com/pistonspeedicalc.html
That'll get you your average piston speed quickly. Then if you know the weight of the piston and convert everything to metric, you can use F= MA to figure out the force the piston experiences at TDC on the exhaust stroke (maximum tension on the rod since there's no combustion chamber pressure canceling out the force from the piston travelling up in the cylinder).
If you do the math, you'll find the difference between a 3.4" stroke and a 3.0" stroke end up only being ~3%. If you're at the bleeding edge, being able to reduce the mass of your rod due to the decreased load might be worth it. Maybe. Or leave the rods along and enjoy the added margin.
But that's just the force of the piston at the end of the rod. The shorter stroke has a rod journal closer to the crank centerline, which moves the rod pin mass inward 0.4" (think of a figure skater pulling their arms in, they spin faster) so it'll take less force to accelerate the crank. That probably has more to do with the destroked engine wanting to rev than the piston speeds.
But if you don't lower the deck height, you'll need a longer rod, and on and on.