When you say the top and bottom of the block, are you talking about the deck? If you measure that much out of square from the intake side of the deck to the exhaust side, the decks are rolled. You can verify a rolled deck if the opposite deck has the same error only in reverse.
When you have rolled decks, The problem is that if you correct that much by squaring the decks, the bores will be off (or not 90 degrees to the new deck surface. This can be corrected but it takes a larger overbore to clean up the cylinders. I would verify the bore position relative to the decks by sweeping the bore up and down with a dial indicator.
I use a CNC machine center to measure deck position relative to the cam bore. If the cam bore is zero degrees the decks should be 45 degrees and -45 degrees from the cam bore. I see many OEM blocks with LOTS of error. Some can effectively be corrected, and some cannnot. For a street engine, a little bit of error won't hurt a thing......the engine doesn't know the difference.