I was running Q16 and alky on a 10.8:1 target. Alky was a little over 10% of the mix. If there was any detonation at those levels the rod bearings would be hammered after one instance. There would be deformation and evidence of crank to bearing contact particularly in the top half of the bearing. A little detonation is not ok. All the rod bearings looked great on tear down.
Let me tell you about my first alcohol engine I put rods through.
Stage II off-center block, stock rods, Arias pistons, stock crank.
I was way off on the fueling target. Too lean, with too much boost. CR was 10.25:1. It was only 30 psi boost, and that should have been just fine for that CR, but the a/f ratio was way too lean. Soon after the car left the line I heard loud knocking. I got off the throttle for a split second. The engine sounded fine. I made the big mistake of getting back into the throttle. Soon, again the knocking came back, escalating in loudness until I heard parts of the camshaft and rods bouncing off the bottom of the car. It happened so fast the second round that I couldn't even react fast enough to get off the throttle before the parts started flying.
This is the video of that pass.
YouTube - Grand National Alky Buick V6 v1.0
Amazingly, the bearings, head gaskets, heads, and piston tops looked perfect. I swear, I could have thrown the bearings in the next engine. I was amazed. I didn't even surface the heads. Just threw them on the next engine, and they're on the present engine now.
There is no question that the engine went into pre-ignition. Yet, the bearings looked perfect. Stock crank, stock journal width.